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New Family Of Anti-cancer Drugs To Be Developed From Synthetic Molecules
by Robert White
10 Jun 2008 at 5:00pm
Synthetic molecules designed by two Hebrew University of Jerusalem researchers have succeeded in reducing and even eliminating the growth of human malignant tissues in mice, while having no toxic effects on normal tissue.The molecules developed by Dr. Arie Dagan and Prof. Shimon Gatt of the Department of Biochemistry of the Hebrew University-Hadassah Medical School affected the ... Click on title for full news .... Prostate Cancer Spread Prevented By Blocking Signaling Protein
by Johnson Smith
10 Jun 2008 at 5:00pm
Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have shown that by blocking a signaling protein, they can prevent prostate cancer cells from metastatic dissemination. The work opens the door to future studies examining the protein as a target for therapies aimed at keeping prostate cancer at bay.In a series of experiments in both the laboratory and animal m... Click on title for full news .... Ancient Riddle Of 'Finger Clubbing' Solved By UK Researchers
by Jennifer Davis
10 Jun 2008 at 5:00pm
A puzzling medical condition, identified more than 2,000 years ago by Hippocrates, has finally been explained by researchers at the University of Leeds.The phenomenon of "finger clubbing", a deformity of the fingers and fingernails, has been known for thousands of years, and has long been recognized to be a sign of a wide range of serious diseases - especially lung cancer."It's ... Click on title for full news .... Type 1 Diabetes In Children Linked With Sun Exposure And Vitamin D Levels
by Monica Tele
10 Jun 2008 at 5:00pm
Sun exposure and vitamin D levels may play a strong role in risk of type 1 diabetes in children, according to new findings by researchers at the Moores Cancer Center at University of California, San Diego (UCSD) and the Department of Family and Preventive Medicine. This association comes on the heels of similar research findings by this same group regarding vitamin D levels and... Click on title for full news .... MRI can help surgeons plan sphincter-sparing surgery in patients with rectal ...
by Monica Tele
10 Jun 2008 at 5:00pm
3T MRI can accurately stage, and help surgeons plan sphincter-sparing surgery in patients with rectal cancer, according to a recent study conducted by researchers at Qilu Hospital of Shandong University in Shandong, China."Recently, MRI has been increasingly accepted by radiologists, surgeons and patients to image the rectum because of its superior soft tissue contrast and multi... Click on title for full news .... Genetically Engineered Functioning T-regs To Treat Autoimmune Disease
by Johnson Smith
8 Jun 2008 at 5:00pm
In autoimmune diseases, the immune system turns against the body's own tissues and organs, wreaking havoc and destruction for no apparent reason. Partly because the origins of these diseases are so obscure, no effective treatment exists, and the suffering they inflict is enormous. Now Weizmann Institute scientists have developed a method that in the future may make it possible t... Click on title for full news .... Melanoma Patients To Benefit Of New Combination Biotherapy
by Johnson Smith
8 Jun 2008 at 5:00pm
The combination of two different biotherapies may be beneficial for patients with inoperable melanoma, according to a University of Pittsburgh Cancer Institute (UPCI) study presented at the 44th annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.Researchers in the melanoma and skin cancer program at UPCI combined two biotherapies -- treatments that st... Click on title for full news .... Kylie Minogue had been a great ambassador for breast cancer awareness
by Jennifer Davis
8 Jun 2008 at 5:00pm
Kylie's breast cancer triggered a surge of over 30 per cent in breast imaging of low risk women, says new University of Melbourne study.Use of mammography and breast ultrasound procedures soared by over 30 per cent among women aged 25-44 in the six months following Kylie Minogue's breast cancer diagnosis, says a new study from the University of Melbourne.There was also a sharp ... Click on title for full news .... High Risk Of Future Health Problems For Survivors Of Childhood Hodgkin's Lymp...
by Lisa Martin
8 Jun 2008 at 5:00pm
Adults who survived childhood Hodgkin's Lymphoma should be especially vigilant about cancer and cardiovascular screenings, according to researchers from Wake Forest University Baptist Medical Center and colleagues.Reporting at the annual meeting of the American Society of Clinical Oncology in Chicago today, Sharon Castellino, M.D., a pediatric oncologist, said a 26-center study... Click on title for full news .... Tumor Suppressor Gene Could Be a New Target For Future Anticancer Drugs
by Johnson Smith
8 Jun 2008 at 5:00pm
Scientists at Cold Spring Harbor Laboratory (CSHL) have taken the search for cancer-causing genes an important step forward. In a newly published paper, they confirm that a gene called DLC1 is a tumor suppressor. They have demonstrated in living mice that its deletion, inactivation or loss precipitates events culminating in an aggressive type of liver cancer closely related to c... Click on title for full news .... Special Schools - Sex and Relationship Education
by Teachers TV
13 May 2008 at 11:30am
Pioneering work on SRE at Shepherd School in Nottingham
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Every Child Matters - Tom's Team
by Teachers TV
6 May 2008 at 10:00am
What happens when children's services don't communicate?
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School Stories - Norway
by Teachers TV
11 Apr 2008 at 6:00am
A Norwegian school shows how it integrates disabled children
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The Teaching Challenge - Comedy Dave
by Teachers TV
26 Mar 2008 at 12:30pm
Comedy Dave leads a group of inner city children on an adventure
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KS1/2 Maths - Learning Maths with Kyane
by Teachers TV
10 Mar 2008 at 5:00am
Follow a lesson on 3D shapes through the eyes of a Year 4 pupil
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KS1/2 Science - Learning Science with Kyane
by Teachers TV
5 Mar 2008 at 4:00am
Examining Year 4 pupil Kyane during a science lesson on friction
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Beautiful Minds - A Little Matter of Gender
by Teachers TV
12 Feb 2008 at 5:00pm
A look at the differences between male and female brains
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School Matters - I am Bovvered
by Teachers TV
12 Feb 2008 at 11:30am
One dedicated teacher takes a huge risk to help troubled girls
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Beautiful Minds - The Einstein Effect
by Teachers TV
5 Feb 2008 at 5:00pm
A fascinating look at the relationship between genius and autism
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Beautiful Minds - Memory Masters
by Teachers TV
29 Jan 2008 at 5:00pm
An exploration into the fascinating world of savants
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When it comes to preventing amputation
28 Nov 2007 at 10:56pm
Scientists at Scholl College's Center for Lower Extremity Ambulatory Research (CLEAR) at Rosalind Franklin University of Medicine and Science, Leiden University in the Netherlands, and Texas AandM University have presented important new information that could help physicians and their patients predict dangerous recurrent wounds that precede amputations in persons with diabetes. The study, conducted over a several-year period, identified two simple items that helped predict recurrence........Potential New Target For Type 2 Diabetes
28 Nov 2007 at 10:56pm
Researchers at the University of Pennsylvania School of Medicine have discovered a potential new target for treating type 2 diabetes, according to a new study that appeared online this week in Nature. The target is a protein, along with its molecular partner, that regulates fat metabolism. ?Over the last 10 years, we have begun to understand the importance of fat metabolism in diabetes,? notes lead author Morris J. Birnbaum, MD, PhD, the Willard and Rhoda Ware Professor of Diabetes and Metabolic Diseases at Penn and an Investigator of the Howard Hughes Medical Institute. ?Type 2 diabetics are at a higher risk for cardiovascular disease because they also have disorders in fat metabolism as a result of obesity and abnormal insulin action.? Birnbaum is also the Associate Director of the Type 2 Diabetes Unit for Penn?s Institute for Diabetes, Obesity, and Metabolism........helping obese diabetics lose weight
28 Nov 2007 at 10:56pm
A plate and cereal bowl with markers for proper portion sizes appear to help obese patients with diabetes lose weight and decrease their use of glucose-controlling medications, according to a report in the June 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. Between 1960 and 2000, the proportion of U.S. adults who were obese increased from 13.4 percent to 30.9 percent, according to background information in the article. Most cases of type 2 diabetes can be attributed directly to obesity. Restricting calories has been shown to improve blood sugar control in diabetics, partially by contributing to weight loss. The increasing prevalence of obesity is paralleled by increasing portion sizes in the marketplace, the authors write. Portion sizes are an important determinant of energy intake; the number of calories ingested by subjects at a meal has been directly correlated with the serving size offered........Cord blood may preserve insulin levels in children with type 1 diabetes
28 Nov 2007 at 10:56pm
Umbilical cord blood may safely preserve insulin production in children newly diagnosed with type 1 diabetes, as per findings from a small national pilot study presented Monday (June 25) at the American Diabetes Associations 67th Scientific Sessions in Chicago. University of Florida scientists sought to determine whether it is feasible to use a patients own cord blood stem cells to neutralize the bodys autoimmune attack on the pancreas and help restore the organs ability to make insulin, which regulates how the body uses sugar and other nutrients for energy........Pharmacists To Help Diabetes Sufferers
28 Nov 2007 at 10:56pm
A new Wesley Research Institute project aims to make it much easier for people to manager their Type 2 Diabetes by using community pharmacists. There are more than one million Australians with Type 2 Diabetes who are at an increased risk of developing serious health problems including heart disease, stroke, kidney disease and blindness........Rosiglitazone for type 2 diabetes
28 Nov 2007 at 10:56pm
New studies are needed to assess the trade-offs between potential benefits and potential harms when rosiglitazone is used by people with type 2 diabetes. This Cochrane Systematic Review analysed data from 18 trials that involved a total of 8432 people and found no evidence that rosiglitazone led to better patient outcomes when compared with other therapies. Diabetic control (as measured by levels of HbA1c) was no better in patients given rosiglitazone when in comparison to other antidiabetic drugs. Patient oriented outcomes such as mortality, diabetes related morbidity, or quality of life were not addressed in most studies........Shielding the brain from too much insulin can prolong life
28 Nov 2007 at 10:56pm
One route to a long and healthy life may be establishing the right balance in insulin signaling in the body and brain, as per new research from Children's Hospital Boston. The study, reported in the July 20 issue of Science, not only reinforces the value of exercising and eating in moderation, but also helps explain a paradox in longevity research........How insulin secreting cells maintain their glucose sensitivity
28 Nov 2007 at 10:56pm
Researchers at the leading Swedish medical university Karolinska Institutet have now disclosed the mystery how the insulin-secreting cells maintain an appropriate number of ATP sensing ion channel proteins on their surface. This mechanism, which is described in the latest number of Cell Metabolism, explains how the human body can keep the blood glucose concentration within the normal range and thereby avoid the development of diabetes........Periodontal diseases and pre-diabetes
28 Nov 2007 at 10:56pm
Periodontal diseases may contribute to the progression to pre-diabetes, as per a new study that appears in the recent issue of the Journal of Periodontology. Pre-diabetes is a condition in which blood glucose levels are higher than normal, but not high enough to be diagnosed as diabetes. The American Diabetes Association estimates 54 million people in the United States have pre-diabetes, and a significant portion of those people will develop Type 2 diabetes within 10 years........Erectile dysfunction in diabetics
28 Nov 2007 at 10:56pm
A new study sheds additional light on how erectile dysfunction (ED) interacts with diabetes. The study is another step in uncovering the link between the two disorders, and may lead to improved efficacy in therapys. The study, "Lack of Central Nitric Oxide Triggers Erectile Dysfunction in Diabetes," was conducted by Hong Zheng, William G. Mayhan, and Kaushik P. Patel, Departments of Cellular and Integrative Physiology; and Keshore R. Bidasee, Department of Pharmacology, University of Nebraska Medical Center, Omaha, NE. The results appear in the March 2007 edition of the American Journal of Physiology Regulatory, Integrative and Comparative Physiology, one of 11 peer-reviewed scientific publications issued monthly by The American Physiological Society (APS) (www.The-APS.org)........Supplement Inhibits Multiple Sclerosis, Type 1 Diabetes
28 Nov 2007 at 10:56pm
A glucosamine-like dietary supplement has been found to suppress the damaging autoimmune response seen in multiple sclerosis and type 1 diabetes mellitus, as per University of California, Irvine health sciences researchers. In studies on mice, Dr. Michael Demetriou and his colleagues with the UC Irvine Center for Immunology observed that N-acetylglucosamine (GlcNAc), which is similar but more effective than the widely available glucosamine, inhibited the growth and function of abnormal T-cells that incorrectly direct the immune system to attack specific tissues in the body, such as brain myelin in MS and insulin-producing cells of the pancreas in diabetes. Findings from the study are published on the online version of the Journal of Biological Chemistry........Illuminating Cause Of Diabetes
28 Nov 2007 at 10:56pm
Any photographer can vouch for the difficulty of capturing a clear picture of a moving target. When it comes to molecules, however, sometimes the motion is exactly what researchers want to see - for example, to understand the pathological protein mis-folding and assembly that seem to underlie a host of human disorders, including diabetes and Alzheimer's disease........How insulin TORC2 blood sugar levels
28 Nov 2007 at 10:56pm
La Jolla, CA With the help of genetically engineered mice whose livers turned into glowing light bulbs, scientists at the Salk Institute for Biological Studies have illuminated the underpinnings of an insidious and growing health concern type II diabetes. In the study reported in the September 5 advanced online edition of Nature, the scientists report that a protein called TORC2 serves as a key biochemical control point linking feeding, insulin, and elevated blood sugar production in the liver. The findings highlight TORC2 and an enzyme called SIK2 as potential drug targets for treating type II diabetes........Sleep apnea may increase risk of diabetes
28 Nov 2007 at 10:56pm
Scientists at the Yale University School of Medicine have observed that patients with obstructive sleep apnea are at increased risk for developing of type II diabetes, independent of other risk factors. The findings are being presented at the American Thoracic Society 2007 International Conference, on Monday, May 21........Transporters and diabetes-related retinal damage
28 Nov 2007 at 10:56pm
Two transporters that deliver alternative energy sources to the eye may help delay retinal damage that can occur in diabetes, scientists say. The transporters, SMCT1 and SMCT2, can circumvent the eye's protective blood-retinal barrier, delivering energy sources lactate and ketone bodies to a healthy eye, says Dr. Pamela Martin, biochemist at the Medical College of Georgia........
